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Cannabidolic Acid (CBDA) – an Unnoticed Bioactive Compound
CBDA, or Cannabidolic acid, is a chemical compound found in the trichomes of uncured cannabis plants. CBDA is the precursor to CBD, and it breaks down from its acid form when heated or aged. Decarboxylation is the process of converting CBDA to CBD.
Cannabidiolic acid (CBDA) is a little-known cannabinoid with major therapeutic potential. CBDA is now seen as the next frontier in cannabinoid-based therapy.
CBDA’s benefits include anti-inflammatory properties, anti-nausea properties, antioxidants, pain relief, anti-bacterial/antimicrobial properties, and antiproliferative properties.
Scientists found out how CBDA impacts serotonin, an important neurotransmitter known for its role in signal transmission between cells that produces feelings like happiness or reward during activities associated with this chemical–but also plays some part in our body’s response to nausea/vomiting among other things!
The cannabinoid activates a receptor in the brainstem known as the 5-HT1A receptor. It is one of the numerous serotonin receptors found on the cell’s surface in humans and animals.
Does CBDA Get You High?
CBDA like CBD does not cause intoxication. Most cannabinoids such as THC and CBD bind to the CB1 and CB2 cannabinoid receptors, but their acidic forms take a separate method.
CBDA interacts with our ECS (endocannabinoid system) by inhibiting the Cox-2 enzyme, which does not directly affect our CNS (central nervous system).
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